Cell-based therapies
Treatment in which stem cells are induced to differentiate into the specific cell type required to repair damaged or depleted adult cell populations or tissues.
Cell culture
Growth of cells in vitro on an artificial medium for experimental research.
Cell division
Method by which a single cell divides to create two cells. This continuous process allows a population of cells to increase in number or maintain its numbers.
Cell type
A specific subset of cells within the body, defined by their appearance, location and function.
i) adipocyte: the functional cell type of fat, or adipose tissue, that is found throughout the body, particularly under the skin. Adipocytes store and synthesize fat for energy, thermal regulation and cushioning against mechanical shock
ii) cardiomyocytes: the functional muscle cell type of the heart that allows it to beat continuously and rhythmically
iii) chondrocyte: the functional cell type that makes cartilage for joints, ear canals, trachea, epiglottis, larynx, the discs between vertebrae and the ends of ribs
iv) fibroblast: a connective or support cell found within most tissues of the body. Fibroblasts provide an instructive support scaffold to help the functional cell types of a specific organ perform correctly.
v) hepatocyte: the functional cell type of the liver that makes enzymes for detoxifying metabolic waste, destroying red blood cells and reclaiming their constituents, and the synthesis of proteins for the blood plasma
vi) hematopoietic cell: the functional cell type that makes blood. Hematopoietic cells are found within the bone marrow of adults. In the fetus, hematopoietic cells are found within the liver, spleen, bone marrow and support tissues surrounding the fe tus in the womb.
vii) myocyte: the functional cell type of muscles
viii) neuron: the functional cell type of the brain that is specialized in conducting impulses
ix) osteoblast: the functional cell type responsible for making bone
x) islet cell: the functional cell of the pancreas that is responsible for secreting insulin, glucogon, gastrin and somatostatin. Together, these molecules regulate a number of processes including carbohydrate and fat metabolism, blood glucose levels and acid secretions into the stomach.
Clone
A line of cells that is genetically identical to the originating cell; in this case, a stem cell.
Cloning
The process in which an organism produces one or more genetically alike copies of itself by asexual means. Cloning may occur by propagation of cuttings, as in the case of plants; continual budding, as in the case of hydra; fission, as in the case of bacteria and protozoa; parthenogenic asexual reproduction as in the case of aphids; or somatic cell nuclear transfer, as in the case of higher order animals such as mammals. The term cloning can also be applied to a group of cells undergoing replication by repetitive mitoses (cell division).
Culture medium
The broth that covers cells in a culture dish, which contains nutrients to feed the cells as well as other growth factors that may be added to direct desired changes in the cells.
Cytoplasm
Is a homogeneous, generally clear jelly-like material that fills cells. The cytoplasm consists of cytosol and the cellular organelles, except the nucleus. The cytosol is made up of water, salts and organic molecules and many enzymes that catalyze reactions.